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Not an actual patient.
Individual results may vary.

About atopic

What is atopic dermatitis (eczema)?

is a type of . In fact, it’s the most common type, affecting more than 16 million adults in the United States.

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Not an actual patient.
Individual results may vary.

Two images comparing normal skin and skin inflamed with atopic dermatitis (eczema)

Chronic inflammation beneath the surface

is a skin disease that’s caused by an overactive . When the is triggered, it causes , and your skin can become itchy, red, and dry.

With , the overactive causes . So even when symptoms aren’t present on your skin, can still be happening under your skin.

Common symptoms of moderate-to-severe eczema include*:

dry/scaly skin impacted by atopic dermatitis (eczema)

Dry or scaly skin

Inflamed darker skin impacted by atopic dermatitis (eczema)

Darkening of the skin

Person scratching their inflamed skin on their arm. Skin is suffering from atopic dermatitis (eczema) symptoms


Thickening of the skin impacted by atopic dermatitis (eczema)

Thickening of the skin

Reddening of the skin on arm impacted by atopic dermatitis (eczema)

Reddening of the skin

Small raised bumps caused by atopic dermatitis (eczema)

Small raised bumps

*Examples of moderate-to-severe ().


can be exhausting and often unpredictable—appearing at different times and on different parts of the body. For adults, most commonly appears on the neck, hands, arms, back of the knees, and inside of the elbows.

The impact of IL-13

While the exact cause of is unknown, we do know that people with have an overactive and a weakened that causes damage to the skin. That overactive produces a number of proteins in the body—one of which is (interleukin-13). is a protein that sends signals that lead to in the skin.

Studies have shown that people with have more in their skin than people without . It’s also been shown that the more people have, the more severe their is.

The itch-scratch cycle

When too much is present in the skin, it leads to continued and unbearable itch. When you scratch your skin, the weakens and becomes more damaged, allowing substances such as bacteria, allergens, and viruses to enter.

When the immune system detects these substances, the body produces more in the skin, starting the vicious cycle again.

Animation of itch scratch cycle Animation of itch scratch cycle Animation of itch scratch cycle

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