Frequently
asked questions

Atopic dermatitisA chronic inflammatory skin disorder that results in itchy, red skin that can crack and bleed. Atopic dermatitis is the most common form of eczema. is a type of eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis.. In fact, it’s the most common type, affecting over 16 million adults in the United States.

EczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis. is a chronicAn illness that is long-lasting or occurs over and over again. skin disease that’s caused by an overactive immune responseA reaction of the complex system of cells to defend the body against foreign substances and infection.. When the immune responseA reaction of the complex system of cells to defend the body against foreign substances and infection. is triggered, it causes inflammationAn immune response your body produces to protect you from bacteria, foreign substances, and infection. In atopic dermatitis, increased levels of inflammation can lead to red, itchy skin., and your skin can become itchy, red, and dry. 

With eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis., the overactive immune responseA reaction of the complex system of cells to defend the body against foreign substances and infection. causes inflammationAn immune response your body produces to protect you from bacteria, foreign substances, and infection. In atopic dermatitis, increased levels of inflammation can lead to red, itchy skin.. So even when symptoms aren’t present on your skin, inflammationAn immune response your body produces to protect you from bacteria, foreign substances, and infection. In atopic dermatitis, increased levels of inflammation can lead to red, itchy skin. can still be happening under your skin.

Learn more about atopic dermatitis

Common symptoms of moderate-to-severe eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis. include:

• Dry or scaly skin
• Darkening of the skin
• Itching
• Thickening of the skin
• Reddening of the skin
• Small raised bumps

EczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis. can be exhausting and often unpredictable—appearing on different parts of the body. For adults, eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis. most commonly appears on the neck, hands, arms, back of the knees, and inside the elbows.

Learn more about the symptoms of eczema

While the exact cause of eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis. is unknown, we do know that people with eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis. have an overactive immune responseA reaction of the complex system of cells to defend the body against foreign substances and infection. and a weakened skin barrierThe skin barrier (also called the epidermis) is the outermost layer of your skin. that causes damage to the skin. That overactive immune responseA reaction of the complex system of cells to defend the body against foreign substances and infection. produces a number of proteins in the body—one of which is IL-13Interleukin 13 (IL-13) is a signaling protein, or cytokine, that plays an important role in the immune response that leads to skin inflammation in atopic dermatitis. (interleukin-13). IL-13Interleukin 13 (IL-13) is a signaling protein, or cytokine, that plays an important role in the immune response that leads to skin inflammation in atopic dermatitis. is a protein that sends signals that lead to inflammationAn immune response your body produces to protect you from bacteria, foreign substances, and infection. In atopic dermatitis, increased levels of inflammation can lead to red, itchy skin. in the skin.

Studies have shown that people with eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis. have more IL-13Interleukin 13 (IL-13) is a signaling protein, or cytokine, that plays an important role in the immune response that leads to skin inflammation in atopic dermatitis. in their skin than people without eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis.. It’s also been shown that the more IL-13Interleukin 13 (IL-13) is a signaling protein, or cytokine, that plays an important role in the immune response that leads to skin inflammation in atopic dermatitis. people have, the more severe their eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis. is.

Learn more about the causes of eczema

When too much IL-13Interleukin 13 (IL-13) is a signaling protein, or cytokine, that plays an important role in the immune response that leads to skin inflammation in atopic dermatitis. is present in the skin, it leads to continued inflammationAn immune response your body produces to protect you from bacteria, foreign substances, and infection. In atopic dermatitis, increased levels of inflammation can lead to red, itchy skin. and unbearable itch. When you scratch your skin, the skin barrierThe skin barrier (also called the epidermis) is the outermost layer of your skin. weakens and becomes more damaged, allowing substances such as bacteria, allergens, and viruses to enter.

When the immune system detects these substances, the body produces more IL-13Interleukin 13 (IL-13) is a signaling protein, or cytokine, that plays an important role in the immune response that leads to skin inflammation in atopic dermatitis. in the skin, starting the vicious cycle again.

Learn more about the itch-scratch cycle

Adbry® (tralokinumab-ldrm) is an injection for adults with moderate-to-severe atopic dermatitisA chronic inflammatory skin disorder that results in itchy, red skin that can crack and bleed. Atopic dermatitis is the most common form of eczema., a type of eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis..

It’s a prescription medicine for those who:

• Don’t get relief from prescription topical therapies
• Can’t use prescription topical therapies

You can use Adbry with and without topical steroids.

Children should not use Adbry.

Learn more about Adbry

Adbry is not a cream, an ointment, or a pill. And it’s not a topical corticosteroidTopical corticosteroids, also known as topical steroids, are creams, ointments, lotions, gels, and foams used for skin conditions that are applied topically (on top of the skin).. It’s a biologicA biologic drug is produced from living organisms or contains components of living organisms. treatment that helps calm the inflammationAn immune response your body produces to protect you from bacteria, foreign substances, and infection. In atopic dermatitis, increased levels of inflammation can lead to red, itchy skin. that leads to the symptoms of eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis..

Adbry works inside the body to help get clearer skin and control the unbearable itch.

Adbry is the first and only biologicA biologic drug is produced from living organisms or contains components of living organisms. injection that specifically targets IL-13Interleukin 13 (IL-13) is a signaling protein, or cytokine, that plays an important role in the immune response that leads to skin inflammation in atopic dermatitis., one of the proteins in the immune system that contributes to skin inflammationAn immune response your body produces to protect you from bacteria, foreign substances, and infection. In atopic dermatitis, increased levels of inflammation can lead to red, itchy skin. in eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis..

Learn more about how Adbry is different

A biologicA biologic drug is produced from living organisms or contains components of living organisms. is a type of medicine that is made from living organisms or components of living organisms.

Learn more about biologics

Adbry works by helping to target and neutralizeWhen you neutralize a substance, it means you make it ineffective. IL-13Interleukin 13 (IL-13) is a signaling protein, or cytokine, that plays an important role in the immune response that leads to skin inflammation in atopic dermatitis.. When IL-13Interleukin 13 (IL-13) is a signaling protein, or cytokine, that plays an important role in the immune response that leads to skin inflammation in atopic dermatitis. is neutralizedWhen you neutralize a substance, it means you make it ineffective., it is unable to send signals that lead to eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis.-related inflammationAn immune response your body produces to protect you from bacteria, foreign substances, and infection. In atopic dermatitis, increased levels of inflammation can lead to red, itchy skin..

Learn more about how Adbry works

Adbry was studied in 3 separate clinical trials of almost 2,000 adults aged 18 and older with moderate-to-severe atopic dermatitisA chronic inflammatory skin disorder that results in itchy, red skin that can crack and bleed. Atopic dermatitis is the most common form of eczema. (eczemaA group of skin conditions that causes itch, inflammation, and rashes. The most common type of eczema is atopic dermatitis.). People in the trials injected 2 prefilled syringes every other week.

TRIAL 1: 601 people used Adbry; 197 used placeboAn inactive substance that contains no medicine.

TRIAL 2: 577 people used Adbry; 193 used placeboAn inactive substance that contains no medicine.

TRIAL 3: 243 people used Adbry + topical corticosteroidsTopical corticosteroids, also known as topical steroids, are creams, ointments, lotions, gels, and foams used for skin conditions that are applied topically (on top of the skin).; 123 used placeboAn inactive substance that contains no medicine. + topical corticosteroidsTopical corticosteroids, also known as topical steroids, are creams, ointments, lotions, gels, and foams used for skin conditions that are applied topically (on top of the skin).

The safety of Adbry was studied in 5 clinical trials.

Learn more about how Adbry was studied

Adbry was proven to help clear skin and reduce itching at 4 months. Explore the full clinical results here.

Learn more about Adbry results

Before using Adbry, tell your healthcare provider about all your medical conditions, including if you:

• have eye problems.
• have a parasitic (helminth) infection.
• are scheduled to receive any vaccinations. You should not receive a “live vaccine” if you are treated with Adbry.
• are pregnant or plan to become pregnant. It is not known whether Adbry will harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known whether Adbry passes into your breast milk and if it can harm your baby.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

For information on how to prepare and inject Adbry, and how to properly store and throw away used Adbry prefilled syringes and syringe covers, download the Instructions for Use

Adbry can cause serious side effects, including:

• Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using Adbry and tell your healthcare professional or get emergency help right away if you get any of the following symptoms:
  • breathing problems
  • itching
  • skin rash
  • swelling of the face, mouth, and tongue
  • fainting, dizziness, feeling lightheaded (low blood pressure)
  • hives
• Eye problems. Tell your healthcare provider if you have any worsening eye problems, including eye pain or changes in vision.

The most common side effects of Adbry include:

• Eye and eyelid inflammationAn immune response your body produces to protect you from bacteria, foreign substances, and infection. In atopic dermatitis, increased levels of inflammation can lead to red, itchy skin., including redness, swelling, and itching
• Injection site reactions
• High count of a certain white blood cell (eosinophilia)

These are not all of the possible side effects of Adbry. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

On the first day of treatment with Adbry, your healthcare professional will give you your initial (or loading) dose of 4 injections. This dose helps start to build up the medicine in your body.

Then, your healthcare professional will show you or your caregiver how to inject Adbry, just under your skin.

After you learn to inject Adbry and receive your loading dose, you will inject 2 prefilled syringes at home every other week.

After 4 months, if you have clear or almost clear skin and weigh under 220 lbs, your healthcare professional may determine if your dose may be changed to 2 prefilled syringes every 4 weeks. Use Adbry exactly as told by your healthcare professional.

Learn more about starting Adbry

Adbry is an injection given under the skin (also known as a subcutaneous injectionAn injection, like Adbry™ (tralokinumab-ldrm), given under the skin.).

Watch Emma’s injection routine with Adbry® (tralokinumab-ldrm). She breaks down the steps and shows you how to properly inject your full maintenance dose of Adbry every other week.

Your healthcare professional will show you or your caregiver how to inject Adbry under your skin.

After you learn to inject Adbry and receive your loading dose of 4 prefilled syringes, you will inject 2 prefilled syringes at home every other week for your maintenance dose.

Always read the Instructions for Use that comes with your Adbry carton before self-injecting.

Learn more about how to inject Adbry

You can choose to inject Adbry in your stomach (abdomen) or thigh. If you prefer to have help from a caregiver, they can inject in your upper arm after a healthcare professional shows them how to do it.

You should inject both syringes in the same area of your body while keeping them at least 1 inch apart.

Remember that each time you inject a new set of injections (every other week), you should rotate and choose a different injection area. Do not use the same body area two times in a row.

Learn more about where to inject Adbry

• Skin is tender
• Skin is damaged
• Bruises or scars are present
• Skin is within 2 inches of your belly button

Learn more about where to avoid injecting Adbry

If you miss a dose, inject the missed dose as soon as possible, then continue with your next dose at your regular scheduled time. If you have any questions, call your healthcare professional.

If you accidentally inject more Adbry than you’re prescribed, call Poison Control at 1-800-222-1222.

Learn more about if you miss a dose

Adbry should be stored in the refrigerator between 36°F and 46°F (or 2°C and 8°C).

Don’t freeze the syringes or use syringes that have been previously frozen.

Like all medicines, Adbry should be kept out of the reach of children.

Remember to remove both syringes from the refrigerator 30 minutes before you are ready to self-inject. Don’t try to speed up this process by warming up the syringes in the microwave, running under hot water, or placing in direct sunlight. Simply let the syringes warm up to room temperature by lying the carton flat on a table or counter out of direct light.

Learn more about storing Adbry

All used syringes and syringe covers should be thrown away in a puncture-resistant Sharps ContainerA hard, rigid container used to safely dispose of syringes and needles..

When your container is almost full, follow your local guidelines for disposal. Depending on where you live, there may be state or local laws to follow.

For more information about safe sharps disposal, and for specific information about disposal in the state where you live, visit the FDA’s website.

Learn more about disposing of Adbry

Adbry is a biologicA biologic drug is produced from living organisms or contains components of living organisms. injection that requires special shipping and handling by a specialty pharmacySimilar to a local pharmacy; however, a specialty pharmacy manages medicines that are complex or that need special handling.. Specialty pharmaciesSimilar to a local pharmacy; however, a specialty pharmacy manages medicines that are complex or that need special handling. are similar to local pharmacies in a number of ways. The major difference between the two is that a specialty pharmacySimilar to a local pharmacy; however, a specialty pharmacy manages medicines that are complex or that need special handling. manages medicines that require special handling (e.g., require refrigeration).

Once you’ve been prescribed Adbry your specialty pharmacySimilar to a local pharmacy; however, a specialty pharmacy manages medicines that are complex or that need special handling. will process your prescription, confirm your shipping address over the phone, and then deliver the medicine to your home by mail.

Ask your healthcare professional about which specialty pharmaciesSimilar to a local pharmacy; however, a specialty pharmacy manages medicines that are complex or that need special handling. are located near you.

The Adbry® Advocate™ Program is here to help you through the process. Call 844-MY-ADBRY (844-692-3279) for help coordinating your Adbry shipment.

Learn more about specialty pharmacies

For information on how to prepare and inject Adbry, and how to properly store and throw away used Adbry prefilled syringes, download the Instructions for Use.

You can also watch this step-by-step Self-Injection Video.

Have questions about Adbry or the self-injection process? Those enrolled in the Adbry® Advocate™ Program can receive virtual injection training upon request. Call 844-MY-ADBRY (844-692-3279) for more information.

Learn more about self-injection resources