How Adbry works
Adbry works inside your body to help calm eczema.
Adbry is not a cream, an ointment, or a pill. And it’s not a topical corticosteroid.
Hope for eczema relief can start with Adbry
Adbry is a biologic injection that targets and neutralizes IL-13
IL-13 is a protein in the immune system that contributes to skin inflammation that leads to eczema symptoms. Biologics are medicines made from living organisms or parts of living organisms.
Normal Skin
Eczema Skin
Skin on Adbry
I was itching day and night. With Adbry, I felt itch relief early on.”
Camrie
A real Adbry patient.
Individual results may vary.
Adbry Clinical Results
Eczema relief is possible
Across Trials 1, 2, and 3, more adults using Adbry saw a
Scroll to see before & after photos
Adults
Adbry was studied in 3 separate clinical trials of almost 2,000 adults aged 18 and older with moderate-to-severe atopic dermatitis (eczema). Adults in the trials injected 2 prefilled syringes every other week.
TRIAL 1: 601 adult patients used Adbry; 197 used placebo
TRIAL 2: 577 adult patients used Adbry; 193 used placebo
TRIAL 3: 243 adult patients used Adbry + topical corticosteroids; 123 used placebo + topical corticosteroids
Clearer skin was measured in 3 ways:
- The percentage of adult patients who saw clear or almost clear skin
- The percentage of adult patients who saw a 75% or better improvement in skin
- The percentage of adult patients who saw a clinically meaningful reduction in itch
Adolescents
Adbry for adolescents (ages 12-17)
If you have a adolescents with moderate-to-severe eczema, your role as a caregiver is an important one. A big part of that is helping to navigate their treatment options. It may help to know that Adbry has been studied in adolescents (ages 12-17) to ensure its safety and test its ability to achieve clearer skin and less itch.
How was Adbry given when treating adolescents (ages 12-17)?
Adolescent patients were treated using Adbry alone, without topical corticosteroids. The clinical trial included 192 patients aged 12-17 with moderate-to-severe eczema, and they were injected with 1 prefilled syringe every other week after their initial loading dose.
TRIAL: 98 adolescents aged 12-17 used Adbry; 94 used placebo
Clearer skin was measured in 2 ways:
- The percentage of adolescent patients who saw clear or almost clear skin
- The percentage of adolescent patients who saw a 75% or better improvement in skin
Trial 3: Adbry + topical corticosteroids vs placebo + topical corticosteroids
Clearer skin and less itch
243 adults used Adbry every other week + topical corticosteroids as needed;
123 adults used placebo every other week + topical corticosteroids as needed.
Clear or almost clear skin
4 Months:
~40% of adults vs 27%
using placebo
8 Months:
89% maintained clear
or almost clear skin
75% or better improvement in skin
4 Months:
56% of adults vs 37%
using placebo
8 Months:
92% maintained a 75% or
better improvement in skin
At 4 Months:
1 out of 2 adults experienced significantly less itch
(vs ~3 out of 10 adults using placebo)
See before & after with Adbry
Before
After
Example of skin improvement in one patient treated with Adbry during a clinical trial. The key outcome was measured at 16 weeks.
Individual results may vary.
Since starting Adbry, it’s been 8 years of calmer skin.”
Beth
A real Adbry clinical trial patient.
Individual results may vary.
The safety of Adbry was studied in 5 clinical trials
Before starting Adbry
Before using Adbry, tell your healthcare provider about all your medical conditions, including if you:
- Have eye problems.
- Have a parasitic (helminth) infection.
- Are scheduled to receive any vaccinations.
You should not receive a “live vaccine” if you are treated with Adbry.
- Are pregnant or plan to become pregnant.
It is not known whether Adbry will harm your unborn baby. - Are breastfeeding or plan to breastfeed.
It is not known whether Adbry passes into your breast milk and if it can harm your baby.
Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
NO warnings of joint pain, psoriasis, psoriasis-related arthritis, or vision problems, including blindness* in the Prescribing Information
NO warnings for redness in the face or shingles in the Prescribing Information
NO lab testing or continued lab monitoring required
*Associated with pink eye, redness and discomfort in the front of the eye, or swollen, irritated eyelids.
